Creatine has become one of the most popular supplements among people looking to improve their fitness and build muscle. It is commonly used by athletes and gym-goers due to its well-documented role in enhancing physical performance. However, in recent years, its use has expanded beyond the gym, with influencers and wellness advocates promoting its potential cognitive benefits, such as improved memory and mental clarity. This has led to increased public interest, but questions remain about the scientific validity of these claims. Creatine is a naturally occurring compound found in the body, primarily in muscles and the brain. It is also present in certain foods, such as meat and fish. The supplement form of creatine is typically derived from synthetic sources and is available in powder or capsule form. It works by increasing the production of ATP, a molecule that provides energy for muscle contractions, which can enhance strength and endurance during exercise. This mechanism is well-supported by scientific research, particularly in the context of physical performance. While the benefits of creatine for muscle building and exercise performance are widely accepted, the evidence regarding its cognitive effects is less clear. Some studies suggest that creatine may improve memory and brain function, particularly in individuals who are deficient in the compound. However, more research is needed to confirm these effects and understand the extent of its impact on cognitive health. Experts emphasize that the current evidence is not yet strong enough to support broad claims about its mental benefits. In a recent discussion, science editor Ian Sample and Dr. Justin Roberts, a professor of nutritional physiology at Anglia Ruskin University, explored the scientific basis of creatine and evaluated the claims surrounding its use. They highlighted the importance of distinguishing between well-established benefits and those that require further investigation. As with any supplement, it is crucial to rely on credible scientific evidence when considering its use for health or performance goals.