Greek singer dies from cardiac arrest

Greek singer Giorgos Mazonakis, 54, died on September 9 after experiencing a cardiac arrest at a private clinic in Athens. He was receiving plasma exchange, a procedure he had chosen for anti-aging purposes.

Plasma exchange and its medical use

Plasma exchange is a medical treatment used in some countries, like France, for specific conditions such as Guillain-Barré syndrome. It involves removing harmful substances from the blood plasma, either by replacing it with an albumin solution or by filtering out toxins.

Scientific research on anti-aging claims

While some studies have explored the effects of plasma exchange on aging, the evidence remains limited. A 2022 study in GeroScience noted a decrease in certain aging-related proteins in a small group of people, but no definitive proof of rejuvenation or extended lifespan was found.

Risks and limitations of the procedure

A 2025 study in Scientific Reports found that plasma exchange without albumin did not lead to cellular rejuvenation and may even speed up aging markers. Experts warn that the removal of beneficial elements like growth factors and anti-inflammatory proteins can lead to serious side effects, including allergic reactions or infections.

Medical professionals caution against the practice

Dr. Catherine de Goursac and Professor Olivier Moranne have both criticized plasma exchange for anti-aging as an unnecessary, costly, and potentially dangerous procedure. They emphasize that it is not a recognized medical treatment and is often used by celebrities seeking unproven beauty or health benefits.