Researchers at MIT have developed a tiny microparticle that can add essential nutrients—iron and iodine—to everyday foods and drinks without altering their taste, color, or texture. This innovation aims to tackle global deficiencies in these vital nutrients, which affect nearly two billion people worldwide. The study, published in the journal Matter in August 2025, was led by scientists from the lab of Ana Jaklenec and Robert Langer at MIT.
The microparticle, called NuMOF, is made from common food ingredients: iron, fumaric acid (a widely used additive), and vitamin C, which helps stabilize the structure. Iodine is embedded within the microparticle’s porous framework. One of the key challenges in adding iron to foods like coffee and tea is that iron can react with polyphenols—compounds found in these drinks—to create a metallic taste and make the iron harder for the body to absorb. The NuMOF structure prevents this reaction, keeping the drink's flavor intact. The microparticle remains stable even in boiling water for over two hours and is too small to be noticed in the mouth, with no detectable taste, color, or texture.
Once ingested, the microparticle dissolves in the acidic environment of the stomach, releasing the iron and iodine for absorption by the body. Animal studies have shown that this method of delivery is as effective as traditional iron supplements. The research team is now working on developing a doubly fortified salt that contains both iron and iodine and is exploring the possibility of launching a startup to commercialize enriched beverages. However, the technology still requires large-scale human trials and approval from health regulatory agencies before it can be widely used.
This development could significantly impact global nutrition, especially in regions where deficiencies in iron and iodine are widespread. By making nutrient fortification more palatable and practical, the microparticle offers a promising new approach to improving public health through everyday food and drink.
MIT Researchers Develop Microparticle to Fortify Foods with Iron and Iodine Without Altering Taste
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