Made In Chelsea star Sam Vanderpump has revealed that his mother and brother are unable to donate their livers to him, which means he must now wait for a liver transplant through the National Health Service (NHS) waiting list. The reality TV personality was diagnosed with end-stage liver disease in October 2025 and had previously hoped that family members could serve as live donors. However, after medical evaluations, it was determined that they are not suitable for live donation, leaving Sam to wait for a transplant from a deceased donor. Sam was born with congenital liver and kidney disease, which has led to significant health challenges. In December 2024, he was hospitalized with severe kidney and liver failure, which resulted in life-threatening sepsis. Now, despite his condition, Sam is not considered a high priority for a transplant because he is not currently in a critical state. People with genetic conditions like his are typically not prioritized for transplants until they become seriously ill, which may mean Sam has to wait even longer for a donor organ. The NHS is currently facing a significant shortage of organ donors, which has caused the waiting list for transplants to reach its longest point ever. According to NHS Blood and Transplant, the number of donors has dropped by 9% compared to the same period last year. As a result, over 8,700 people are now waiting for a life-saving organ donation, and nine people die each week while waiting for a transplant. This shortage has prompted the NHS to launch an urgent response plan to address the crisis. Sam has been actively encouraging the public to register as organ donors, highlighting the urgent need for more people to come forward. He emphasized that there are more people in need of organs than those willing to donate. Registering as an organ donor can also ease the burden on families during a time of grief, as they won’t have to make the difficult decision on behalf of a loved one. NHS Blood and Transplant is urging one million people who have never registered as donors to confirm their decision, as the rate of family consent for organ donation has dropped from 67% in 2020/21 to 57% last year. Anthony Clarkson, the organization’s director, stressed that the decline in donors and the rising number of people waiting for transplants require urgent action and collective effort across the NHS and society.