Sexual side effects from antidepressants are common but often overlooked. UK's MHRA urges patients to discuss these issues with their doctors rather than stopping treatment.
Sexual side effects from antidepressants
Sexual side effects from antidepressants can occur, but they are often not discussed. According to a report, these issues may include changes in desire, erections, orgasm, or ejaculation. UK medicines agency updates information
On October 15, 2026, the UK medicines agency, the MHRA, announced an enhancement of the information provided to patients about antidepressants. The message emphasizes that patients should not stop their treatment on their own but should discuss these issues with the doctor managing their care. Side effects may appear at different stages
The sexual effects reported under antidepressants can appear after the introduction of treatment, after a change in dosage, or when switching medications. The MHRA's safety information also notes that some sexual problems may persist after stopping certain treatments. Not all patients are affected
However, it is clarified that not all patients will be affected, and antidepressants should not be avoided when necessary. The agency emphasizes that sexuality is part of a drug's tolerance and should be addressed like any other side effect. Depression also impacts sexuality
Dr. Gérald Kierzek notes that depression itself can disrupt sexuality, with factors such as loss of drive, fatigue, anxiety, sleep disturbances, low self-esteem, or relationship difficulties also playing a role. Therefore, the medication is not automatically the sole cause of these issues.
