Chemsex refers to the deliberate use of psychoactive substances during sexual activity, aimed at enhancing pleasure, prolonging encounters, or improving performance. The practice involves specific drugs and is often associated with extended sexual sessions. According to Houssem Eddine Bouasla, a pharmacist in Grenoble and co-author of a 2026 study on the topic, chemsex differs from general drug use in its focus on sexual experiences. Catherine Delorme, president of the Federation Addiction, describes it as involving "true sexual marathons" with particular substances. The public became aware of chemsex in 2023 through the Pierre Palmade affair, but the practice has existed for some time, particularly among men who have sex with men (MSM). This group is broader than the LGBT community, as it includes men who may identify as heterosexual but engage in sexual activity with other men. Julien Martinez, an advanced practice nurse, notes that chemsex is not limited to any specific social or geographic group. A 2022 report estimated that 20% of MSM in France are affected, and a 2026 update confirmed a similar prevalence of 22%, though accurate data remains difficult to obtain due to the hidden nature of the practice. Experts like Houssem Eddine Bouasla suggest that chemsex is linked to the social stigma, homophobia, and harassment faced by sexual and gender minorities, which can lead to a search for pleasure and connection. Jean-Patrick Fabre, a former user and founder of the Chems Pause association, describes chemsex as a way to escape a "deep sense of unease." Catherine Delorme acknowledges that while some people may enjoy chemsex, many feel shame and internalize societal stigma, believing they are not fully respectable. The substances used in chemsex include synthetic cathinones, GHB and GBL, methamphetamine, ketamine, and cocaine, each carrying significant health risks such as cardiac issues, heat stroke, and overdose. Pharmacists, however, are often poorly trained to address the topic. A 2025 study found that while 80% of pharmacists had heard of chemsex, many lacked the knowledge or tools to help patients. Experts recommend approaching patients with openness and kindness, especially those on HIV prevention medication or seeking harm reduction resources. The Ministry of Health has taken steps to address the issue, including a 2026-2030 roadmap that includes specific initiatives for chemsex. However, challenges remain, including the separation between addiction care and sexual health services. Advocates call for depenalization of drug use to reduce stigma and encourage people to seek support. Resources such as hotlines and specialized centers are available for those affected. Read The chemsex phenomenon, Brahim Bouselmi, Emmanuel Cannou, ed. Les petits matins, September 2026.