A large review of 87 clinical trials suggests that eating four to six servings of whole grains each day could offer significant benefits for heart health. Published in the European Heart Journal on September 15, the study found that higher whole grain consumption is linked to improvements in body weight, blood pressure, cholesterol levels, and blood sugar. These changes could help reduce the long-term risk of heart disease.
The research was led by Dr. Helda Tutunchi from Tabriz University of Medical Sciences in Iran. While previous studies have shown a connection between whole grain intake and better heart health in the general population, results from clinical trials have been inconsistent. This new study aimed to determine the specific amount of whole grains needed to achieve meaningful cardiovascular benefits.
The analysis included over 6,500 participants from clinical trials across Asia, Europe, the United States, Canada, Australia, and Brazil. Those who ate more whole grains had lower body weight, smaller waist measurements, and reduced blood pressure. They also had lower levels of total cholesterol, "bad" LDL cholesterol, triglycerides, blood sugar, and interleukin-6, a marker of inflammation in the body.
The benefits were noticeable even with a daily intake of 30 to 40 grams of whole grains, but the most significant improvements were seen with 60 to 100 grams per day—about four to six servings. In practical terms, this could include a bowl of oatmeal, a sandwich with whole grain bread, and a serving of brown rice. Dr. Tutunchi emphasized that this is the most comprehensive review of its kind, evaluating not only the effects of whole grains but also the amount needed for the best results. High-certainty evidence was found for improvements in weight, waist size, and total cholesterol.
However, most of the trials were relatively short, lasting about eight weeks on average. It is still unclear whether these benefits last over the long term. Additionally, few studies looked at very high whole grain intakes—over 140 grams per day—so the effects of such high amounts remain unknown. The researchers also note that the trials mainly measured risk factors like cholesterol and blood pressure, not actual heart events like heart attacks or strokes. More long-term studies are needed to confirm if these improvements lead to fewer cardiovascular diseases.
In an accompanying editorial, Dr. Cecilie Kyrø from the Danish Cancer Institute explained that whole grains are cereal grains that retain all three main parts—bran, germ, and endosperm—in their natural proportions. The review found strong evidence that consuming 60–100 grams of whole grains daily leads to measurable improvements in heart-related health markers. While current U.S. dietary guidelines recommend 2–4 servings of whole grains a day, the study suggests that higher intakes might be more beneficial for overall cardiometabolic health.
Study Suggests Optimal Whole Grain Intake for Cardiovascular Benefits
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