A prostate cancer test known as the Stockholm3, which helped detect the condition in TV presenter Jeremy Clarkson, will soon be available to 10,000 men in London. This test is considered more effective than the traditional PSA (prostate-specific antigen) test in identifying aggressive forms of prostate cancer. Men aged between 44 and 74 will be able to access the £99 test, which looks at multiple biological markers to better determine if a man has a more dangerous type of prostate cancer. The Stockholm3 has been available in private clinics since 2023 but has typically cost hundreds of pounds for patients. Earlier European research found that the test detected up to 90% of clinically significant prostate cancers, compared to just 42% with the PSA test. The initiative is being led by the not-for-profit organisation Central London Healthcare as part of a private screening programme. Around 8,000 men will be able to access the test at a reduced cost, while an additional 2,000 men who may not be able to afford it will receive the test for free. The service will initially be offered at Nuffield Health’s Barbican Medical Centre in London. Earlier this year, the UK National Screening Committee advised against widespread screening using the PSA test, stating it could cause more harm than good. Instead, it recommended that only a few thousand high-risk men—those with a specific gene mutation—should be screened. The Transform trial, supported by Prostate Cancer UK and the National Institute for Health and Care Research (NIHR), is currently investigating whether broader population testing should be considered. Jeremy Clarkson is among several high-profile individuals advocating for the government to "change the story on prostate cancer" and review current testing guidelines. Clarkson revealed that his cancer was first detected by a PSA test, but it was the more advanced Stockholm3 test that confirmed the diagnosis. Prostate cancer is the most common cancer in men in the UK, with over 55,000 new cases diagnosed each year and around 12,300 deaths annually. In a letter published in the Daily Mail, Clarkson joined with figures such as Sir Stephen Fry, former Prime Ministers Lord David Cameron and Rishi Sunak, and others to urge the new health secretary, Yvette Cooper, to establish a national screening programme. The letter argued that many high-risk men currently lack guaranteed access to potentially life-saving tests. The signatories, including film director Sir Steve McQueen and businessman Nick Jones, stated that unless a man has a specific genetic variant, there is no clear pathway to testing beyond hoping a general practitioner will take their concerns seriously. They argued that this situation is not acceptable.