A recent study, involving canoeing along nearly 800 kilometers of the Rhône River, has uncovered the presence of per- and polyfluoroalkyl substances (PFAS), often referred to as forever chemicals due to their extreme persistence in the environment. These substances are known for their resistance to degradation, which makes them a long-term concern for environmental and human health. The study, led by Rémi Camus from Lyon, included setting up 52 sampling stations and testing for 50 types of PFAS. Of these, 14 were found at levels exceeding safety thresholds at least once. The findings, published and reported by Le Progrès, revealed that trifluoroacetic acid (TFA), a particularly persistent PFAS compound, was detected throughout the entire route. In some areas, such as the Rhône valley and near Lyon, concentrations reached as high as 1,000 nanograms per liter. The research identifies Lyon, especially its southern sector, as a critical point in the river’s contamination. This area is home to the "chemistry valley," where companies like Arkema and Daikin operate. The study suggests that both urban and industrial activities contribute to the increased presence of various PFAS molecules after the river flows south of Lyon. Specific PFAS compounds, such as PFHxA, which was used by Daikin until the end of 2025, and 6:2 FTAB, commonly found in fire-fighting foams, appear more frequently in the Rhône starting from the chemistry valley. Additionally, PFOA and PFOS—two substances now banned due to their potential health risks—are also more prevalent in this region. Authorities have been warning residents since 2022 not to consume fish caught near Pierre-Bénite, a town close to the river, due to concerns about contamination. This caution is supported by the findings of the recent study. In addition, a separate study conducted around Lyon has also detected forever chemicals in the air, highlighting the widespread nature of PFAS pollution in the area. These findings underscore the need for continued monitoring and regulation of PFAS to protect both the environment and public health.