This weekend's Premier League fixtures feature several high-profile matches with notable injury updates across the teams involved. Newcastle United will host Bournemouth at St James’ Park at 12:30pm on TNT Sports 1. Newcastle faces several injury concerns, with players like Joelinton and Burn sidelined due to thigh and ankle issues, respectively. Bournemouth also has multiple players on the sidelines, including Kroupi and Araujo, who are out with foot and thigh injuries. At 3pm, Brentford will welcome Sunderland to Gtech Community Stadium. Brentford’s injury list includes Van den Berg and Milambo, both with knee problems, while Sunderland’s Diarra is out with a hamstring injury. Meanwhile, Brighton will take on Leeds at the Amex Stadium. Brighton has several players injured, including Mitoma and Hinshelwood, while Leeds has Rodon and Joseph sidelined with hamstring and knee issues, respectively. Fulham will host Crystal Palace at Craven Cottage at 3pm. Fulham’s Cairney is out with a knee injury, and Crystal Palace has Mateta, Riad, and Sarr all sidelined with hamstring, knee, and groin issues. Manchester City will face Coventry at the Etihad Stadium, with Doku injured due to a calf issue, while Coventry has three players out with hamstring, knee, and thigh injuries. Later in the afternoon, Nottingham Forest will host Tottenham at City Ground. Forest has Savona injured with a knee problem, while Tottenham faces multiple injury concerns, including Simons, Kulusevski, and Odobert, all with knee issues. Tottenham’s Maddison and Savinho are also doubtful due to shoulder and muscle injuries. The day concludes with a match between Hull and Aston Villa at 5:30pm on Sky Sports Premier League, where both teams have multiple players sidelined or suspended. Finally, Everton will host Manchester United at 2pm, with both teams dealing with various injury concerns, and Arsenal will face Chelsea at 4:30pm, where several players are also out with injuries or doubts about their fitness.