At toilets, many people consider wet wipes to be cleaner than regular paper. The feeling of freshness is reassuring, and the packaging promises softness and hygiene. However, on the most fragile part of the body, this comfort comes at a cost, and the old dry toilet paper remains often the safest option. Dermatologists from the North American Contact Dermatitis Group found that wet wipes have become a frequent cause of skin allergies, especially around the anus. Their analysis, published in 2017 in Dermatitis, showed that these products contain preservatives, fragrances, and cleaning agents that can irritate sensitive mucous membranes. In contrast, plain toilet paper that is soft and unscented is less likely to damage the skin barrier. Proctologist Evan Goldstein, who runs the Bespoke Surgical clinic in New York, sees patients who have skin irritation from what they thought was a harmless habit. One common cause is methylisothiazolinone, a preservative that can trigger redness, itching, and eczema. The skin in this area is thin and poorly protected, making it vulnerable to repeated exposure to these chemicals. As wet wipes have become more common in homes, so have the related skin issues. Moisture also plays a role, as it can linger in warm, poorly ventilated folds of skin. This environment encourages harmful bacteria to grow and disrupt the natural bacteria that protect the skin. Small cracks may form, and conditions like hemorrhoids can worsen. Even wipes labeled as chemical-free can be problematic, since trapped water can continue to cause issues. The area never fully recovers if it stays constantly wet. The safest toilet paper is soft, white, and unscented, as dyes and fragrances can irritate the skin. The way you use the paper matters as much as the product itself. Rubbing too hard can scratch the skin instead of cleaning it. It is better to gently dab with light pressure, avoiding repeated rubbing. Overzealous cleaning can actually harm the skin by stripping away its natural protective layer. Cleaning too thoroughly can leave the area raw and more sensitive to future contact. In some cases, this has led to what some proctologists call an "over-polished" anus, where the skin is overly sensitive. Goldstein suggests using water, either through a bidet or a showerhead, followed by gentle drying. This method removes residue without rubbing, preserving the skin's natural barrier. Some urologists believe this can also help reduce recurrent urinary tract infections in women. In addition to health benefits, wet wipes also pose environmental concerns. They can clog sewers when they mix with fats and release microplastics into water supplies. Switching to soft, unscented toilet paper or using water instead can help solve both personal and environmental issues.