A large-scale study conducted over nearly ten years among half a million people in the United Kingdom suggests a link between moderate coffee consumption and longevity. This analysis, published in 2018, followed more than half a million participants for about ten years, allowing researchers to cross-reference consumption habits with the evolution of cardiovascular, cerebral, and general health of the volunteers. The findings indicate that moderate coffee consumption appears to offer protective benefits for both the body and the brain. The study highlights a ceiling of up to eight cups per day as a high limit compatible with a reduction in the risk of mortality. However, other more recent studies have suggested that three cups per day may be the true golden number of moderation, with an estimated gain in life expectancy of about two years. These studies also explored additional benefits, such as less sedentary behavior, delayed physical fragility in the elderly, and potential protective effects against neurodegenerative diseases. Researchers note that the time of day when coffee is consumed is almost as important as the quantity. Consumers who limit their coffee intake to the morning show a longer life expectancy and a reduced risk of heart disease, while afternoon consumption may disrupt circadian rhythms and the secretion of hormones such as melatonin or cortisol. Switching to decaffeinated coffee does not change this effect, confirming that the time of day plays a more important role than caffeine itself. Experts recommend avoiding coffee in the afternoon to preserve restorative sleep. However, each organism reacts differently to caffeine, depending on genetics, individual sensitivity, or pre-existing pathologies, making it risky to generalize the same threshold for everyone. The study underscores the importance of moderation and good timing in coffee consumption, suggesting that these factors may be the true allies of beneficial consumption.