A study published in the journal Nature on December 10, 2025, suggests that many mental disorders share parts of the same genes, potentially changing the understanding of mental health and guiding new therapeutic approaches. The research, led by the international consortium Cross-Disorder Psychiatric Genomics, analyzed genetic data from more than one million patients with psychiatric disorders compared to those without a diagnosis. The study covers 14 mental disorders, including schizophrenia, bipolar disorders, depression, anxiety, anorexia nervosa, obsessive-compulsive disorder (OCD), autism, and ADHD. The study found that most genetic influences are not specific to a single disorder, with the same DNA variations increasing the risk of developing several forms of mental disorders. Researchers identified large genetic sets, or "families," grouping several diagnoses. For example, anorexia nervosa and OCD share mechanisms related to compulsive behaviors, while depression and anxiety belong to the same set called "internalized." Autism and ADHD relate to a neurodevelopmental group. Schizophrenia and bipolar disorders, often perceived as very different, present a strong genetic proximity, suggesting common biological vulnerabilities. The study indicates that the same genetic base can be expressed differently according to the environment, experience, cerebral development, and other biological factors. The authors emphasize that these results do not invalidate current diagnoses, which remain essential for guiding care and treatments. The study also notes that genes increase the risk but do not determine alone the appearance of a disorder, with psychological, social, and environmental factors playing a central role. This research opens the way to a more integrated approach to mental health, potentially helping to better understand why certain disorders coexist, guiding research toward treatments targeting common mechanisms, and contributing to reducing the stigma of mental illnesses. The findings highlight the complex interplay between genetics and environment in mental health, offering new perspectives for future studies and clinical practices.